Localization of the oncogene c-erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17.

Abstract

Using in situ hybridization, c-erbA1 has been mapped immediately distal to the translocation breakpoint on chromosome 17 in fibroblasts with a karyotype 46,XX, t(15;17)(q22;q11). Previous work has shown that c-erbA1 is proximal to the translocation breakpoint on chromosome 17 in the t(15;17)(q22;q12-21) in acute promyelocytic leukaemia. The oncogene can… (More)

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@article{Sheer1985LocalizationOT, title={Localization of the oncogene c-erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17.}, author={Daniel P. Sheer and Devon M. Sheppard and M J Le Beau and Jessica Rowley and Carlos M San Rom{\'a}n and E. Solomon}, journal={Annals of human genetics}, year={1985}, volume={49 Pt 3}, pages={167-71} }