• DOI:10.1016/0091-6749(78)90320-2
Corpus ID: 2732758

Localization of the guinea pig eosinophil major basic protein to the core of the granule

@article{Lewis1978LocalizationOT,
  title={Localization of the guinea pig eosinophil major basic protein to the core of the granule},
  author={D. Lewis and J. Lewis and D. Loegering and G. Gleich},
  journal={The Journal of Cell Biology},
  year={1978},
  volume={77},
  pages={702 - 713}
}

D. Lewis, J. Lewis, +1 author G. Gleich

Published 1978

Medicine

The Journal of Cell Biology

The localization of the guinea pig eosinophil major basic protein (MBP) within the cell was investigated by the use of immunoelectron microscopy and by isolation of the granule crystalloids. First, by immunoperoxidase electron microscopy, we found that the MBP of eosinophil granules is contained within the crystalloid core of the granule. Specific staining of cores was present when rabbit antiserum to MBP was used as the first stage antibody in a double antibody staining procedure, whereas… CONTINUE READING

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