Localization of the alpha(1F) calcium channel subunit in the rat retina.

  title={Localization of the alpha(1F) calcium channel subunit in the rat retina.},
  author={Catherine W. Morgans},
  journal={Investigative ophthalmology & visual science},
  volume={42 10},
PURPOSE The molecular identity of the calcium channels that mediate glutamate release from photoreceptors is unknown. Mutations in the recently identified, retina-specific alpha(1F) calcium channel subunit cause incomplete X-linked congenital stationary night blindness (CSNB2), the phenotype of which is consistent with a defect in neurotransmission within the retina. The purpose of this study was to determine the cellular distribution of the alpha(1F) subunit in the retina. METHODS Antibodies… CONTINUE READING
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