Localization of the Salmonella typhimurium flagellar switch protein FliG to the cytoplasmic M-ring face of the basal body.

@article{Francis1992LocalizationOT,
  title={Localization of the Salmonella typhimurium flagellar switch protein FliG to the cytoplasmic M-ring face of the basal body.},
  author={Noreen R Francis and Vera M. Irikura and Shigeru Yamaguchi and David J Derosier and Robert M. Macnab},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 14},
  pages={6304-8}
}
The direction of rotation of the bacterial flagellum is determined by the flagellar switch. We have localized FliG, one of the switch proteins of Salmonella typhimurium, to the cytoplasmic face of the M ring of the flagellar basal body. This localization was made possible by the discovery of two spontaneous mutants in which the fliF (M ring) and fliG (switch) genes were fused in-frame. In the first mutant, a deletion of 7 base pairs at the 3' end of fliF resulted in an essentially full-length… CONTINUE READING
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