Localization of the DER/flb protein in embryos: implications on the faint little ball lethal phenotype.

@article{Zak1990LocalizationOT,
  title={Localization of the DER/flb protein in embryos: implications on the faint little ball lethal phenotype.},
  author={Naomi B. Zak and R J Wides and Eyal D. Schejter and Erez Raz and Ben-Zion Shilo},
  journal={Development},
  year={1990},
  volume={109 4},
  pages={865-74}
}
Antibodies were raised against the Drosophila EGF receptor homolog (DER) and used for immunohistochemical analyses of Drosophila embryos. We found that DER is localized in a wide array of embryonic tissues, displaying a dynamic pattern of expression. DER appears to be expressed in all cells at the cellular blastoderm and gastrula stages. In extended-germ-band embryos, it is found predominantly in the mesoderm and the head. Finally, in retracted-germ-band embryos, DER immunoreactivity is most… CONTINUE READING