Localization of superoxide dismutase activity in rat tissues.

  title={Localization of superoxide dismutase activity in rat tissues.},
  author={Wilma M. Frederiks and Klazien S. Bosch},
  journal={Free radical biology & medicine},
  volume={22 1-2},
Superoxide anion radicals have been implicated in a variety of pathological processes. Under physiological conditions, superoxide dismutase (SOD) is effectively able to disproportionate superoxide anions into hydrogen peroxide and dioxygen. Until now, no techniques have been available to localize SOD activity within tissues. In the present study, SOD activity was detected in different rat tissues using a thin film of xanthine oxidase between the glass slide and the unfixed cryostat section and… CONTINUE READING


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