Localization of sequences regulating ancestral and acquired sites of esterase6 activity in Drosophila melanogaster.

@article{Healy1996LocalizationOS,
  title={Localization of sequences regulating ancestral and acquired sites of esterase6 activity in Drosophila melanogaster.},
  author={Marion J. Healy and Mira M. Dumancic and A. Cao and John G Oakeshott},
  journal={Molecular biology and evolution},
  year={1996},
  volume={13 6},
  pages={784-97}
}
We have broadly defined the DNA regions regulating esterase6 activity in several life stages and tissue types of D. melanogaster using P-element-mediated transformation of constructs that contain the esterase6 coding region and deletions or substitutions in 5' or 3' flanking DNA. Hemolymph is a conserved ancestral site of EST6 activity in Drosophila and the primary sequences regulating its activity lie between -171 and -25 bp relative to the translation initiation site: deletion of these… CONTINUE READING

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