Localization of seminal plasma transforming growth factor-beta1 on human spermatozoa: an immunocytochemical study.

@article{Chu1996LocalizationOS,
  title={Localization of seminal plasma transforming growth factor-beta1 on human spermatozoa: an immunocytochemical study.},
  author={T. Ming Chu and Mary Alice Nocera and Kathleen C. Flanders and Elzbieta Kawinski},
  journal={Fertility and sterility},
  year={1996},
  volume={66 2},
  pages={327-30}
}
OBJECTIVE To localize immunocytochemically transforming growth factor beta1 (TGF-beta1) in human spermatozoa. DESIGN Incubation of spermatozoa with anti-TGF-beta1 antiserum at various pH. SETTING Human volunteers in an academic research institute. PATIENTS Young healthy fertile men. INTERVENTIONS Semen specimens were collected. RESULTS At neutral pH and at physiological pH of seminal plasma, TGF-beta1 immunostaining was detected predominantly at the postacrosomal region of the head… CONTINUE READING

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