Localization of recurrent medullary thyroid carcinoma with technetium-99m-methoxyisobutylnitrile scintigraphy: a case report.

@article{Odriscoll1991LocalizationOR,
  title={Localization of recurrent medullary thyroid carcinoma with technetium-99m-methoxyisobutylnitrile scintigraphy: a case report.},
  author={Caitriona M O'driscoll and Fiona Baker and Murray Joseph Casey and Graham Duffy},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1991},
  volume={32 12},
  pages={2281-3}
}
This case report demonstrates the successful localization of metastatic medullary thyroid carcinoma with 99mTc-labeled methoxyisobutylnitrile (MIBI). Disease recurrence was initially localized using 201Tl and by immunoscintigraphy with 111In-labeled anti-carcinoembryonic antigen (anti-CEA) antibody fragments. Scintigraphy with 99mTc-MIBI yielded higher target-to-background ratios than 201Tl or 111In-anti-CEA. Technetium-99m-MIBI may be a useful agent in the localization of recurrent medullary… CONTINUE READING