Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.

@article{Brenman1998LocalizationOP,
  title={Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.},
  author={Jay E. Brenman and J. Rick Topinka and Edward C. Cooper and Aaron W McGee and Jane Rosen and T R Milroy and Henry J Peter Ralston and David S. Bredt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 21},
  pages={8805-13}
}
Postsynaptic density-93 (PSD-93)/Chapsyn-110 is a member of the membrane-associated guanylate kinase (MAGUK) family of PDZ domain-containing proteins. MAGUKs are widely expressed in the brain and are critical elements of the cytoskeleton and of certain synapses. In the ultrastructural studies that are described here, PSD-93 localizes to both postsynaptic densities and dendritic microtubules of cerebellar Purkinje neurons. The microtubule localization is paralleled by a high-affinity in vivo… CONTINUE READING
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Bredt DS (1996a) Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and a-1 syntrophin mediated by PDZ motifs. Cell 84:757–767

  • JE Brenman, DS Chao, +7 authors SC Froehner
  • 1996
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