Localization of p27kip1 in the developing avian retina: sustained expression in the mature tissue.

Abstract

p27kip1 is a cyclin/CDK inhibitor that is expressed in cells that exit cell cycle and turn post-mitotic. Here, we characterized the expression and localization of p27kip1 during the development of the chick embryo retina. Expression of p27kip1 in this tissue begins at embryonic day 5 (E5), increasing as development proceeds. In contrast to the expression in… (More)
DOI: 10.1016/j.neulet.2009.09.046

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