Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease

@article{Hefti1989LocalizationON,
  title={Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease},
  author={Franz Hefti and Deborah C. Mash},
  journal={Neurobiology of Aging},
  year={1989},
  volume={10},
  pages={75-87}
}
NGF receptors were visualized in human brain sections with an immunohistochemical procedure using a monoclonal antibody. This method results in the selective visualization of a population of neurons in the medial septal nucleus, the nucleus of the diagonal band of Broca, and the nucleus basalis of Meynert. Several lines of evidence indicate that this neuronal population is identical to the cholinergic neurons of the basal forebrain. NGF receptor immunohistochemistry therefore represents a… CONTINUE READING

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Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's disease? An autoradiographic study in the human striatum and basal forebrain.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1992
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