Localization of mRNA for neural cell adhesion molecule (N-CAM) polypeptides in neural and nonneural tissues by in situ hybridization.

@article{Prieto1989LocalizationOM,
  title={Localization of mRNA for neural cell adhesion molecule (N-CAM) polypeptides in neural and nonneural tissues by in situ hybridization.},
  author={Anne L. Prieto and Kathryn L Crossin and Bruce A. Cunningham and Gerald M. Edelman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 23},
  pages={9579-83}
}
The differential expression of the mRNA for the neural cell adhesion molecule (N-CAM) has been studied by in situ hybridization and compared with protein localization analyzed by immunohistochemical staining. The distribution of mRNA during chicken embryonic development was analyzed in neural and nonneural tissues by using an RNA probe that detects all N-CAM mRNAs and a probe specific for the mRNA of the large cytoplasmic domain (ld) of N-CAM. The results provide a detailed description of the… CONTINUE READING

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