Localization of lipoprotein lipase to discrete areas of the guinea pig brain

@article{Vilar1990LocalizationOL,
  title={Localization of lipoprotein lipase to discrete areas of the guinea pig brain},
  author={Sen{\'e}n Vilar{\'o} and Lydia Camps and Manuel Reina and Je{\'u}s P{\'e}rez-Clausell and M. C. Nicolau Llobera and Thomas Olivecrona},
  journal={Brain Research},
  year={1990},
  volume={506},
  pages={249-253}
}
Lipoprotein lipase is a key enzyme in lipoprotein metabolism present primarily in extrahepatic tissues with high turnover of fatty acids. Using immunocytochemistry we have explored where lipoprotein lipase is localized in guinea pig brain. The enzyme was found to be associated with neuronal cells and vascular endothelial surfaces. The distribution was strikingly uneven with intense reaction in some areas, and virtually no reaction in adjacent areas. The highest reactivity was in neocortex, in… CONTINUE READING
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