Localization of hypothalamic insulin receptor in neonatal chicks: evidence for insulinergic system control of feeding behavior.

@article{Shiraishi2011LocalizationOH,
  title={Localization of hypothalamic insulin receptor in neonatal chicks: evidence for insulinergic system control of feeding behavior.},
  author={Jun-ichi Shiraishi and Hiroshi Tanizawa and Masanori Fujita and Shin-ichi Kawakami and Takashi Bungo},
  journal={Neuroscience letters},
  year={2011},
  volume={491 3},
  pages={177-80}
}
Feeding behavior is managed by various neuropeptides and/or neurotransmitters within the central nervous system in vertebrates. It is proposed that central insulin acts as the negative-feedback regulator of appetite via the central melanocortin system in neonatal chicks. The present study investigated the localization of insulin receptors in the chick hypothalamus using immunohistochemistry. Immunostaining revealed hypothalamic neuron expressing insulin receptors in the paraventricular nucleus… CONTINUE READING
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