Localization of hydrogen-bonds within modules in barnase.

  title={Localization of hydrogen-bonds within modules in barnase.},
  author={Takasi Noguti and Hiroyuki Sakakibara and Mitiko Gō},
  volume={16 4},
Proteins in eukaryotes are composed of structural units, each encoded by discrete exons. The protein module is one such structural unit; it has been defined as the least extended or the most compact contiguous segment in a globular domain. To elucidate roles of modules in protein evolution and folding, we examined roles of hydrogen bonds and hydrophobic cores, as related to the stability of these modules. For this purpose we studied barnase, a bacterial RNase from Bacillus amylolique-faciens… CONTINUE READING