Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease.

@article{Levy1989LocalizationOH,
  title={Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease.},
  author={Elizabeth R Levy and John Francis Powell and Veronica J. Buckle and Y. P. Hsu and Xandra O Breakefield and Ian W. Craig},
  journal={Genomics},
  year={1989},
  volume={5 2},
  pages={368-70}
}
A cDNA for the neurotransmitter-degrading enzyme monoamine oxidase-A (MAO-A) has been assigned by in situ hybridization to the human X chromosome and subregionally localized to Xp11.23-11.4. As restriction fragments detected by this probe are deleted in some patients with Norrie disease, this assignment provides confirmation of the localization of the disease.