Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues.

@article{Lawn2001LocalizationOH,
  title={Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues.},
  author={Richard M. Lawn and David P. Wade and Tracey L Couse and Josiah N. Wilcox},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2001},
  volume={21 3},
  pages={378-85}
}
The present study examines the expression of ATP-binding cassette transporter 1 (ABC1) mRNA in normal and atherosclerotic tissues by using in situ hybridization in an effort to better understand the function of this cholesterol transport protein. Samples of normal baboon tissues as well as human normal and atherosclerotic aortas were hybridized with (35)S-labeled ABC1 sense and antisense riboprobes. Widespread expression of ABC1 was observed generally in tissues containing inflammatory cells… CONTINUE READING

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