• DOI:10.1038/320084A0
Corpus ID: 4310476

Localization of gene for human p53 tumour antigen to band 17p13

@article{Isobe1986LocalizationOG,
  title={Localization of gene for human p53 tumour antigen to band 17p13},
  author={M. Isobe and B. Emanuel and D. Givol and M. Oren and C. Croce},
  journal={Nature},
  year={1986},
  volume={320},
  pages={84-85}
}

M. Isobe, B. Emanuel, +2 authors C. Croce

Published 1986

Biology, Medicine

Nature

Recently the gene for the cellular tumour antigen p53, a phos-phoprotein found in increased concentration in a variety of human cells1, has been mapped to region 17q22 by in situ hybridization techniques and has been shown to translocate to the chromosome carrying the translocation [t(15 ; 17)] associated with acute pro-myelocytic leukaemia (APL)2. Based on this finding it has been postulated that this gene has a role in the pathogenesis of APL2. Here we present evidence that the gene for p53… CONTINUE READING

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