Localization of four antigenic sites involved in Venezuelan equine encephalomyelitis virus protection

@article{Agapov1994LocalizationOF,
  title={Localization of four antigenic sites involved in Venezuelan equine encephalomyelitis virus protection},
  author={Eugene V. Agapov and Ivan A Razumov and I. V. Frolov and A. A. Kolykhalov and Sergei V. Netesov and Valery B. Loktev},
  journal={Archives of Virology},
  year={1994},
  volume={139},
  pages={173-181}
}
Stable neutralization and protection escape variants of a virulent strain (Trinidad Donkey) of the VEE virus were selected by monoclonal antibodies (MAbs). Determination of nucleotide sequences of nine variants revealed a clustering of single mutations in four regions of the E1 and E2 glycoproteins. Involvement of amino acid residues 206 (site E1-1), 57 and 59 (site E2-2), 180, 182, 213, 214 and 216 (site E2-6) and 232 (site E2-3) in protective epitopes was demonstrated. 

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Investigation of the antigenic structure of Venezuelan equine encephalomyelitis virus using monoclonal antibodies. I. Preparation of hybridomas and the antigenic structrue of the glycoprotein El

  • IA Razumov, EV Agapov, AV Pereboev, EV Protopopova, SD Lebedeva, VB Loktev
  • The Current Topics of Science and Technic,
  • 1992
Highly Influential
4 Excerpts

Investigation of receptor region of Venezuelan equine encephalomyelitis virus by means of monoclonal antibodies

  • IA Razumov, AV Pereboev, +6 authors VB Loktev
  • Voprosy Virusologii
  • 1991
Highly Influential
4 Excerpts

The complete nucleotide sequence of the Eastern equine encephalitis virus genome. Molekuiarnaya Genetika, Microbiologiya i Virusologiya 5:8-15 [in Russian] Authors' address

  • VolchkovVE, VA Volchkova, Netesov
  • Institute of Molecular Biology,
  • 1994
1 Excerpt

Mapping of Venezuelan equine encephalomyelitis virus glycoprotein E2 sites E2-2 and E2-6 using peptides

  • VA Svyatchenko, AV Pereboev, +5 authors VB Loktev
  • Voprosy Virusologii
  • 1993
1 Excerpt

The comparison of nucleotide and deduced structural proteins sequence virulent and attenuated

  • IV Frolov, AA Kolykhalov, VE Volckov, SV Netesov, LS Sandakhchiev
  • Docl Akad Nauk SSSR
  • 1991
1 Excerpt

The complete nucleotide sequence of the Eastern equine encephalitis virus genome

  • VA Volchkova, SV Netesov
  • 1991

Similar Papers

Loading similar papers…