Localization of estrogen receptors-and-and androgen receptor in the human growth plate at different pubertal stages

@inproceedings{Nilsson2003LocalizationOE,
  title={Localization of estrogen receptors-and-and androgen receptor in the human growth plate at different pubertal stages},
  author={Ola Nilsson and Dionisios Chrysis and Olli Pajulo and Anders Boman and Mikael Holst and Joanna Rubinstein and E. Martin Ritz{\'e}n and Lars S{\"a}vendahl},
  year={2003}
}
Sex steroids are required for a normal pubertal growth spurt and fusion of the human epiphyseal growth plate. However, the localization of sex steroid receptors in the human pubertal growth plate remains controversial. We have investigated the expression of estrogen receptor (ER) , ER and androgen receptor (AR) in biopsies of proximal tibial growth plates obtained during epiphyseal surgery in 16 boys and eight girls. All pubertal stages were represented (Tanner stages 1–5). ER , ER and AR were… CONTINUE READING