Localization of dopamine receptors in the tree shrew brain using [3H]-SCH23390 and [125I]-epidepride.

@article{Mijnster1999LocalizationOD,
  title={Localization of dopamine receptors in the tree shrew brain using [3H]-SCH23390 and [125I]-epidepride.},
  author={M. Janneke Mijnster and E Isovich and Gabriele Fl{\"u}gge and Eberhard Fuchs},
  journal={Brain research},
  year={1999},
  volume={841 1-2},
  pages={101-13}
}
The tree shrew is a mammalian species, which is phylogenetically related to insectivores and primates. The aim of the present study was to investigate the distribution of dopamine receptor D1- and D2-like binding sites in the brain of this non-rodent, non-primate mammal. Using in vitro autoradiography and employing the radioligands [3H]-SCH23390 and [125I]-epidepride, dopamine receptors were mapped and quantified. Significant findings with regard to the D1-like binding pattern include the… CONTINUE READING