Localization of cofilin mRNA to the leading edge of migrating cells promotes directed cell migration.

Abstract

mRNA trafficking, which enables the localization of mRNAs to particular intracellular targets, occurs in a wide variety of cells. The importance of the resulting RNA distribution for cellular functions, however, has been difficult to assess. We have found that cofilin-1 mRNA is rapidly localized to the leading edge of human lung carcinoma cells and that… (More)
DOI: 10.1242/jcs.163972

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@article{Maizels2015LocalizationOC, title={Localization of cofilin mRNA to the leading edge of migrating cells promotes directed cell migration.}, author={Yael Maizels and Froma Oberman and Rachel Miloslavski and Nava Ginzach and Malka Berman and Joel K. Yisraeli}, journal={Journal of cell science}, year={2015}, volume={128 10}, pages={1922-33} }