Localization of coenzyme Q10 in the center of a deuterated lipid membrane by neutron diffraction.

@article{Hau2005LocalizationOC,
  title={Localization of coenzyme Q10 in the center of a deuterated lipid membrane by neutron diffraction.},
  author={Thomas Hau\ss and Silvia Dante and Thomas Haines and Norbert A. Dencher},
  journal={Biochimica et biophysica acta},
  year={2005},
  volume={1710 1},
  pages={57-62}
}
Quinones (e.g., coenzyme Q, CoQ10) are best known as carriers of electrons and protons during oxidative phosphorylation and photosynthesis. A myriad of mostly more indirect physical methods, including fluorescence spectroscopy, electron-spin resonance, and nuclear magnetic resonance, has been used to localize CoQ10 within lipid membranes. They have yielded equivocal and sometimes contradictory results. Seeking unambiguous evidence for the localization of ubiquinone within lipid bilayers, we… CONTINUE READING