Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human.

@article{MacDonald1990LocalizationOC,
  title={Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human.},
  author={Paul N. MacDonald and Dean Bok and David E. Ong},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 11},
  pages={4265-9}
}
Brain is not generally recognized as an organ that requires vitamin A, perhaps because no obvious histologic lesions have been observed in severely vitamin A-deficient animals. However, brain tissue does contain cellular vitamin A-binding proteins and a nuclear receptor protein for retinoic acid. In the present study, immunohistochemical techniques were used to determine the cell-specific location of cellular retinol-binding protein in human and rat brain tissue. Cellular retinol-binding… CONTINUE READING

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Proc . Jpn . Acad . 65 B , 9 - 12

  • M. Maden, D. E. Ong, +4 authors M. C. Nguyen-Huu
  • Proc . Nati . Acad . Sci . USA
  • 1989

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