Localization of cannabinoid CB1 receptors in the human anterior eye and retina.

@article{Straiker1999LocalizationOC,
  title={Localization of cannabinoid CB1 receptors in the human anterior eye and retina.},
  author={Alex Straiker and Gerald Maguire and Ken Mackie and Jason Lindsey},
  journal={Investigative ophthalmology & visual science},
  year={1999},
  volume={40 10},
  pages={2442-8}
}
PURPOSE To determine the presence and distribution of CB1 cannabinoid receptors within the human eye. METHODS A subtype-specific affinity-purified polyclonal antibody to the cannabinoid CB1 receptor was used to determine CB1 localization. Postmortem human eyes were fixed in methacarn and embedded in paraffin. Sagittal sections were mounted on slides and immunostained using antibodies to the CB1 receptor. Antibody binding was detected either by using peroxidase conjugated secondary antibodies… CONTINUE READING

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