Localization of antigen-presenting cells in Helicobacter pylori-infected gastric mucosa.

@article{Suzuki2002LocalizationOA,
  title={Localization of antigen-presenting cells in Helicobacter pylori-infected gastric mucosa.},
  author={Tatsuhiko Suzuki and Katsuaki Kato and Shuichi Ohara and Kenji Noguchi and Hitoshi Sekine and Hiroshi Nagura and Tooru Shimosegawa},
  journal={Pathology international},
  year={2002},
  volume={52 4},
  pages={265-71}
}
Helicobacter pylori (HP) infection is known to induce the specific immune response in the gastric mucosa. The immune response is triggered by presentation of antigen peptides on the major histocompatibility assembly of the antigen-presenting cells (APC) with the assistance of costimulatory molecules such as B7-1 (CD80) and B7-2 (CD86). Their counter-receptors or ligands on T cells are CD28 or cytotoxic lymphocyte-associated molecule-4. The aim of the present study was to clarify the… CONTINUE READING