Localization of alpha-tocopherol transfer protein in rat brain.

  title={Localization of alpha-tocopherol transfer protein in rat brain.},
  author={Akira Hosomi and Koaru Goto and Hisatake Kondo and Takeshi Iwatsubo and Takanori Yokota and Masaharu Ogawa and Masanori Arita and Junken Aoki and Hiroyuki Arai and Kinji Inoue},
  journal={Neuroscience letters},
  volume={256 3},
Vitamin E (alpha-tocopherol) is a fat-soluble antioxidant that is transported by plasma lipoproteins in the body. Alpha-tocopherol transfer protein (alpha-TTP), which was identified as a product of the causative gene for familial isolated vitamin E (FIVE) deficiency, is a cytosolic liver protein which plays an important role in the efficient circulation of plasma vitamin E in the body. In the present study, we detected the message for alpha-TTP at low levels in some rat tissues including brain… CONTINUE READING


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