Localization of a thrombin-sensitive calcium pool in platelets.

@article{Sato1975LocalizationOA,
  title={Localization of a thrombin-sensitive calcium pool in platelets.},
  author={Tetsuji Sato and Lawrence Herman and John A. Chandler and Alfred Stracher and Thomas C. Detwiler},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1975},
  volume={23},
  pages={103 - 106}
}
Electron microscopic x-ray microprobe analysis of pyroantimonate precipitates in platelets fixed in osmium tetroxide-pyroantimonate revealed calcium localization in the nucleoids of alpha-granules. This pool of calcium had largely disappeared within 10 sec after stimulation of platelets by thrombin. Such a rapid change suggests that this calcium pool may have a regulatory role in stimulus-response coupling. 

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