Localization of a novel autosomal recessive nonsyndromic hearing impairment locus DFNB65 to chromosome 20q13.2–q13.32

@article{Tariq2006LocalizationOA,
  title={Localization of a novel autosomal recessive nonsyndromic hearing impairment locus DFNB65 to chromosome 20q13.2–q13.32},
  author={Aamira Tariq and Regie Lyn P. Santos and Mohammad Nasim Khan and Kwanghyuk Lee and Muhammad Jawad Hassan and Wasim Ahmad and Suzanne M. Leal},
  journal={Journal of Molecular Medicine},
  year={2006},
  volume={84},
  pages={484-490}
}
Autosomal recessive nonsyndromic hearing impairment (ARNSHI) is the most frequent form of prelingual hereditary hearing loss in humans. Between 75 and 80% of all nonsyndromic deafness is inherited in an autosomal recessive pattern. Using linkage analysis, we have mapped a novel gene responsible for this form of nonsyndromic hearing impairment, DFNB65, in a consanguineous family from the Azad Jammu and Kashmir regions, which border Pakistan and India. A maximum multipoint LOD score of 3.3 was… 

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