Localization of a new enteric non-A, non-B [HEV] virus in target organ liver

@article{Gupta2007LocalizationOA,
  title={Localization of a new enteric non-A, non-B [HEV] virus in target organ liver},
  author={H Gupta and Bhanu Iyenger and Badri Nath Tandon},
  journal={Gastroenterologia Japonica},
  year={2007},
  volume={28},
  pages={46-50}
}
SummaryThirteenMacaca mulatta monkeys were used for transmission of enteric non-A, non-B hepatitis virus (HEV) by the portal vein (PV) route. All these animals developed changes which are found in selflimiting acute viral hepatitis e.g. rise in liver enzymes, the presence of HEV specific viral particles in the stool and histological changes in the liver from 21 to 45 days after HEV inoculation. All the animals recovered completely as reflected by normalization of liver enzymes, and regenerative… 
2 Citations
Metabonomic analysis of hepatitis E patients shows deregulated metabolic cycles and abnormalities in amino acid metabolism
TLDR
Findings may help better understand the clinical and biochemical manifestations in this disease and the underlying pathophysiologic processes and it would be worthwhile determining whether patients with hepatitis E are more prone to develop lactic acidosis and ketosis compared with other forms of viral hepatitis.

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