Localization of a high threshold potassium channel in the rat cochlear nucleus.

  title={Localization of a high threshold potassium channel in the rat cochlear nucleus.},
  author={Teresa M Perney and Leonard K Kaczmarek},
  journal={The Journal of comparative neurology},
  volume={386 2},
Potassium channels play a major role in determining the pattern and frequency of neuronal firing. In the cochlear nucleus (CN), various morphologically defined types of neurons have different responses to a sound. We have previously identified one type of cloned K+ channel, termed Kv3.1, which is highly expressed in many auditory neurons. Expression studies indicate that Kv3.1 channels have an unusually high threshold for activation. In this study, we used both in situ hybridization and… CONTINUE READING


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