Localization of TFF3 peptide to porcine conjunctival goblet cells

  title={Localization of TFF3 peptide to porcine conjunctival goblet cells},
  author={Wolfgang Jagla and Antje Wiede and Werner Hoffmann},
  journal={Cell and Tissue Research},
 TFF-peptides (formerly P-domain peptides, trefoil factors) form a new family of mucin-associated peptides mainly in the gastrointestinal tract. TFF3 is a typical secretory product of intestinal goblet cells and occurs also in the respiratory tract. Here, polyclonal antisera specific for TFF3 were used in Western blot analysis and immunofluorescence to determine the presence and distribution of TFF3 in the porcine conjunctiva, which is the primary source for ocular mucins. Significant… CONTINUE READING


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