Localization of Shiga toxins of enterohaemorrhagic Escherichia coli in kidneys of paediatric and geriatric patients with fatal haemolytic uraemic syndrome.

@article{Chaisri2001LocalizationOS,
  title={Localization of Shiga toxins of enterohaemorrhagic Escherichia coli in kidneys of paediatric and geriatric patients with fatal haemolytic uraemic syndrome.},
  author={Urai Chaisri and Masaki Nagata and Hisao Kurazono and Hiroshi Horie and Pongsri Tongtawe and Hideki Hayashi and Takeshi Watanabe and Pramaun Tapchaisri and Manas Chongsa-nguan and Wanpen Chaicumpa},
  journal={Microbial pathogenesis},
  year={2001},
  volume={31 2},
  pages={59-67}
}
Haemolytic uraemic syndrome (HUS) is characterized by haemolytic anaemia, thrombocytopenia and renal failure. Infection with enterohaemorrhagic Escherichia coli (EHEC), mainly O157:H7, has been strongly implicated as the major cause of HUS in children. The pathogenesis of HUS caused by the infection is not well understood and the defined sites of Stx in kidney of EHEC-infected humans has not been clearly demonstrated. The aim of this study was to investigate and compare the locations of Stx… CONTINUE READING