Localization of RANK, RANKL and osteoprotegerin during healing of surgically created periodontal defects in sheep.


BACKGROUND AND OBJECTIVE Modeling of periodontal bone regeneration in a large animal enables better examination of the spatial and temporal regulation of osteogenesis and the remodeling of the healing defect. RANK, RANKL and osteoprotegerin (OPG) are known to be important regulators of bone healing. The aim of this study was to create periodontal defects… (More)
DOI: 10.1111/jre.12196

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