Localization of IL-8 and complement components in lesional skin of psoriasis vulgaris and pustulosis palmaris et plantaris.


BACKGROUND Munro's microabscesses are a characteristic histopathologic feature of psoriasis vulgaris; however, the pathomechanisms underlying the migration of transepidermal leukocytes (PMNs) have not been fully elucidated yet. OBJECTIVE AND METHODS Since the lesional scale extracts contain potent chemoattractants, such as IL-8 and C5a fragments, we… (More)


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