Localization of Corticoliberin Receptors in the Rat Brain

  title={Localization of Corticoliberin Receptors in the Rat Brain},
  author={Elena Rybnikova and Markku Pelto-Huikko and V. V. Rakitskaya and V. G. Shalyapina},
  journal={Neuroscience and Behavioral Physiology},
In situ hybridization was used to study the distribution of corticoliberin receptors of subtypes 1 and 2 (CL-R1 and CL-R2 respectively) in different structures of the rat brain. Levels of CL-R1 mRNA in the brain were significantly greater than levels of CL-R2 mRNA, and the most intense expression of the CL-R1 gene was seen in forebrain structures, especially various neocortical, archicortical, and paleocortical regions in the cerebellar cortex. In addition, significant levels of CL-R1 mRNA… CONTINUE READING