Localization of ADAMTS13 to the stellate cells of human liver.

@article{Uemura2005LocalizationOA,
  title={Localization of ADAMTS13 to the stellate cells of human liver.},
  author={Masahito Uemura and Kouko Tatsumi and Masanori Matsumoto and Masao Fujimoto and Tomomi Matsuyama and Masatoshi Ishikawa and Taka-aki Iwamoto and Toshio Mori and Akio Wanaka and Hiroshi Fukui and Yoshihiro Fujimura},
  journal={Blood},
  year={2005},
  volume={106 3},
  pages={
          922-4
        }
}
Although the chromosomal localization (9q34) of the gene encoding the human form of ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13) and its exclusive expression in the liver have been established, the cells that produce this enzyme are yet to be determined. We investigated the expression of ADAMTS13 mRNA and protein in fresh frozen specimens obtained during liver biopsies of 8 patients with liver diseases. In situ hybridizations to localize ADAMTS13 mRNA… Expand
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