Localization of 17 beta-hydroxysteroid dehydrogenase throughout gestation in human placenta.

@article{Dupont1991LocalizationO1,
  title={Localization of 17 beta-hydroxysteroid dehydrogenase throughout gestation in human placenta.},
  author={Eric Dupont and Fernand Labrie and Van Luu-The and Georges Pelletier},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1991},
  volume={39 10},
  pages={1403-7}
}
17 beta-Hydroxysteroid dehydrogenase (17 beta-HSD) is the enzyme responsible for the formation of all sex steroids in gonadal as well as extragonadal tissues. To obtain more information about the age-specific expression of 17 beta-HSD in the human placenta, we have localized this enzyme by immunocytochemistry at the light microscopic level at different periods of gestation. In the 7- and 9-week-old placenta, immunostaining was detected exclusively in the cytoplasm of the syncytiotrophoblast… CONTINUE READING