Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat.

  title={Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat.},
  author={Jean Ren{\'e} Cazalets and Michel Borde and F Clarac},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={15 7 Pt 1},
An in vitro preparation of newborn rat isolated brainstem/spinal cord was used in order to locate the spinal network responsible in mammals for producing patterned locomotor activity. The spinal cord was partitioned by building Vaseline walls at various lumbar levels. When a mixture of serotonin and N-methyl-D,L-aspartate was bath applied to the upper lumbar cord (L1/L2 segments), rhythmic locomotor-like activity was induced and recorded in all the lumbar segments (from L1 to L5). Conversely… CONTINUE READING
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