Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure.

@article{Yasue1994LocalizationAM,
  title={Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure.},
  author={Hirofumi Yasue and Mitsuisa Yoshimura and Hitoshi Sumida and Ken-ichiro Kikuta and Kiyotaka Kugiyama and Michihisa Jougasaki and Hiroshi Ogawa and Kenji Okumura and Masashi Mukoyama and Kazuwa Nakao},
  journal={Circulation},
  year={1994},
  volume={90 1},
  pages={
          195-203
        }
}
BACKGROUND B-type or brain natriuretic peptide (BNP) is a novel natriuretic peptide secreted from the heart that forms a peptide family with A-type or atrial natriuretic peptide (ANP), and its plasma level has been shown to be increased in patients with congestive heart failure. This study was designed to examine the sources and mechanisms of the secretion of BNP in comparison with those of ANP in control subjects and in patients with heart failure. METHODS AND RESULTS We measured the plasma… CONTINUE READING

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