Localization and function of Bam protein require the benign gonial cell neoplasm gene product.

@article{Lavoie1999LocalizationAF,
  title={Localization and function of Bam protein require the benign gonial cell neoplasm gene product.},
  author={C A Lavoie and Benjamin Ohlstein and Dennis M. McKearin},
  journal={Developmental biology},
  year={1999},
  volume={212 2},
  pages={405-13}
}
Division of a female Drosophila stem cell produces a daughter stem cell and a cystoblast. The cystoblast produces a syncytial cluster of 16 cells by precisely four mitotic divisions and incomplete cytokinesis. Mutations in genes required for cystoblast differentiation, such as bag-of-marbles, block syncytial cluster formation and produce a distinctive "tumorous" or hyperplastic germ cell phenotype. In this paper, we compare the oogenic phenotype of benign gonial cell neoplasm mutations to that… CONTINUE READING

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