Localization and diurnal expression of mRNA encoding the β1-adrenoceptor in the rat pineal gland: an in situ hybridization study


The rat pinealocyte is stimulated by norepinephrine, which is released from sympathetic nerve fibers innervating the gland. Norepinephrine binds to β1-adrenoceptors situated on the pinealocyte cell membrane. Ligand binding to these receptors exhibits a diurnal rhythm, with the largest number occurring in the late part of the light phase when the release of… (More)
DOI: 10.1007/s004410050813

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