Localization and characterization of PACAP receptors in the rat cerebellum during development: evidence for a stimulatory effect of PACAP on immature cerebellar granule cells.

@article{Basille1993LocalizationAC,
  title={Localization and characterization of PACAP receptors in the rat cerebellum during development: evidence for a stimulatory effect of PACAP on immature cerebellar granule cells.},
  author={Magali Basille and Bruno J. Gonzalez and Philippe Leroux and Lydie Jeandel and Alain Fournier and Hubert Vaudry},
  journal={Neuroscience},
  year={1993},
  volume={57 2},
  pages={329-38}
}
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are abundant in the brain and particularly in the cerebellum of adult rats. In contrast, the occurrence of PACAP binding sites has not been investigated during ontogenesis. The aim of the present study was to determine the distribution and biochemical characteristics of PACAP binding sites in the rat cerebellum during postnatal development, and to examine the effect of PACAP on immature cerebellar granule cells… CONTINUE READING