Localization and biosynthesis of aminopeptidase N in pig fetal small intestine.

@article{Danielsen1995LocalizationAB,
  title={Localization and biosynthesis of aminopeptidase N in pig fetal small intestine.},
  author={E Michael Danielsen and Gert Helge Hansen and L-L Niels-Christiansen},
  journal={Gastroenterology},
  year={1995},
  volume={109 4},
  pages={1039-50}
}
BACKGROUND & AIMS Little is known about the expression of brush border enzymes in fetal enterocytes. The aim of this study was to describe the localization and biosynthesis of porcine fetal aminopeptidase N. METHODS This study was performed using histochemistry and immunoelectron microscopy and [35S]methionine labeling of cultured mucosal explants. RESULTS Enzyme activity was present in the brush border membrane and extended into the apical cytoplasm. The protein was colocalized with… CONTINUE READING