Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin

@article{Carlton1995LocalizationAA,
  title={Localization and activation of glutamate receptors in unmyelinated axons of rat glabrous skin},
  author={Susan M. Carlton and Gregory L. Hargett and Richard E. Coggeshall},
  journal={Neuroscience Letters},
  year={1995},
  volume={197},
  pages={25-28}
}
Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the periphery
TLDR
The presence of glutamate receptors on large‐diameter myelinated axons suggests that these mechanosensitive receptors, presumably transducing touch and pressure, may also respond to local glutamate and thus be chemosensitive.
Peripheral Glutamate Receptors Are Required for Hyperalgesia Induced by Capsaicin
TLDR
The results reveal that the activation of iGluRs and group I mGluR in peripheral afferent nerves play an important role in mechanisms whereby capsaicin evokes/maintains nociceptive responses.
Glutamate Receptors and Nociception
TLDR
Inhibition of glutamate release, or of glutamate receptors, in the spinal cord or periphery attenuates both acute and chronic pain in animal models and similar benefits have been seen in studies involving humans (both patients and volunteers); however, results have been inconsistent.
Role of peripheral N-methyl-D-aspartate (NMDA) receptors in visceral nociception in rats.
TLDR
Peripheral NMDA receptors are important in normal visceral pain transmission, and may provide a novel mechanism for development of peripheral sensitization and visceral hyperalgesia.
Activation of Excitatory Amino Acid Receptors in Bovine Dental Pulp Evokes the Release of iCGRP
TLDR
The results suggest that the activation of AMPA and kainate receptors in dental pulp may contribute to peripheral release of vasoactive neuropeptides which mediate a neurogenic component of inflammation.
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