Localization, anchoring, and functions of protein kinase C isozymes in the heart.

@article{MacKay2001LocalizationAA,
  title={Localization, anchoring, and functions of protein kinase C isozymes in the heart.},
  author={Karen Lynn MacKay and Daria Mochly-Rosen},
  journal={Journal of molecular and cellular cardiology},
  year={2001},
  volume={33 7},
  pages={1301-7}
}
Although protein kinase C (PKC) was identified more than 20 years ago, and is involved in a wide variety of essential cellular processes, assigning specific roles to each PKC isozyme has proved difficult. Results over the last few years have suggested that much of the specificity of activated PKC isozymes is attributed to their subcellular localization bringing them into close proximity to a subset of substrates. Our laboratory has taken advantage of the importance of PKC localization and… CONTINUE READING

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