Localisation of the myotonic dystrophy locus to 19q13.2–19q13.3 and its relationship to twelve polymorphic loci on 19q

@article{Harley2005LocalisationOT,
  title={Localisation of the myotonic dystrophy locus to 19q13.2–19q13.3 and its relationship to twelve polymorphic loci on 19q},
  author={H. Harley and K. Walsh and S. Rundle and J. D. Brook and M. Sarfarazi and M. Koch and J. Floyd and P. Harper and D. Shaw},
  journal={Human Genetics},
  year={2005},
  volume={87},
  pages={73-80}
}
  • H. Harley, K. Walsh, +6 authors D. Shaw
  • Published 2005
  • Biology, Medicine
  • Human Genetics
  • SummaryThe order of fourteen polymorphic markers localised to the long arm of human chromosome 19 has been established by multipoint mapping in a set of 40 CEPH (Centre d'Étude de Polymorphisme Humain, Paris) reference families. We report here the linkage relationship of the myotonic dystrophy (DM) locus to twelve of these markers as studied in 45 families with DM. The resulting genetic map is supported by the localisation of the DNA markers in a panel of somatic cell hybrids. Ten of the twelve… CONTINUE READING
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