Localisation of opticin in human proliferative retinal disease.

  title={Localisation of opticin in human proliferative retinal disease.},
  author={David M. Pattwell and Carl Michael Sheridan and M{\'e}lanie Le Goff and Paul N. Bishop and Paul Hiscott},
  journal={Experimental eye research},
  volume={90 3},
This study sought to determine the distribution of opticin, an extracellular matrix small leucine-rich repeat protein secreted by the non-pigmented ciliary body epithelium (CBE), in pathological eye tissues including posterior hyaloid membranes (PHM) and epiretinal membranes (ERM) from subjects with proliferative diabetic retinopathy (PDR), central retinal vein occlusion (CRVO) and proliferative vitreoretinopathy (PVR). Eight enucleated eyes and eleven surgically excised PHMs/ERMs from patients… CONTINUE READING
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Opticin inhibits angiogenesis in the oxygen-induced retinopathy model

  • P. N. Bishop, M. M. Le Goff, +4 authors R. Mayne
  • Invest. Ophthalmol. Vis. Sci
  • 2007
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