Localisation of lanosterol 14α-demethylase in round and elongated spermatids of the mouse testis: an immunoelectron microscopic and stereological study

Abstract

Lanosterol 14α-demethylase (CYP51) is a microsomal cytochrome P450 enzyme involved in the postsqualene cholesterol biosynthetic pathway. CYP51 removes 14α-methyl group from lanosterol], forming FF-MAS (folicular fluid meiosis activating sterol) which accumulates in gonads. The goal of our study is to determine the expression of CYP51 protein in the male… (More)
DOI: 10.1007/s004240100011

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